Peru, which is home to the world¡¯s largest population of alpacas, hopes to develop a vaccine to prevent and control acute forms of the disease in the animals.
Many young alpacas succumb to Pasteurella multocida pneumonia and, according to Abelardo Lenin Maturrano Hern¨¢ndez, until now ¡°there is no research on a specific vaccine to combat the effects of this disease in alpacas¡±.
Dr Hern¨¢ndez is the research project coordinator of a programme based at the National University of San Marcos, and partly funded by Peru¡¯s production ministry through its Innovate Peru Program, which aims to develop the vaccine for young and baby alpacas.
¡°We produced a complete genome sequence of Pasteurella multocida to develop an effective solution against pneumonia in alpacas,¡± explained Dr Hern¨¢ndez, and then ¡°initiated a search for virulence and/or pathogenicity factors that would act as immunogens¡±.
By using ¡°reverse vaccinology techniques¡±, they were able to create a recombinant vaccine designed to bolster alpacas¡¯ defences against bacterial pathogens causing the respiratory illness.
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